![]() nystatin may also be used for purposes not listed in this medication guide. Clotrimazole troches are effective, less expensive, and easier to self-administer than nystatin oral suspension. Comparing Print Nystatin Alternatives Compared Nystatin Diflucan (fluconazole) Fluconazole Prescription only Prescribed for Gastrointestinal Candidiasis, Oral Thrush. The cost of clotrimazole troches in the prophylactic doses given in this study was approximately one tenth that of nystatin oral suspension. For best results, it must be used regularly and as directed. Reasons given for withdrawal were the unpleasant taste of the drugs, or an inability to comply with the protocol. Nystatin is an oral suspension used to treat oral thrush or yeast infection of the mouth. It can also be administered orally with a lozenge or a swish-and-swallow solution. Keep the liquid in your mouth for as long as possible. ![]() Nystatin can be applied topically with an ointment, cream, or powder. Swish it around the mouth, gargle, and swallow or spit out as directed. One patient chose to withdraw from the clotrimazole group, and eight patients withdrew from the nystatin group before completing 60 days of therapy ( P =.002). Summary Nystatin is an antifungal medication that is used to treat candidiasis, also called a yeast infection or thrush. Oral thrush is a yeast infection of the mouth caused by uncontrolled growth of an organism called Candida albicans. It was evident that Fluconazole was more cost effective than oral Nystatin suspension in the treatment of oral candidiasis. ![]() Adverse effects were infrequently seen in either group (one case of mild nausea in the clotrimazole group and three cases in the nystatin group). Both regimens were 100% effective in preventing the development of thrush in the patients studied. The two groups were comparable in age, sex, type of transplant, and amount of immunosuppression. Sixty assessable patients were randomized to receive either clotrimazole troches (n = 32) or nystatin oral suspension (n = 28) for a 60-day period after receiving a renal allograft. This study was performed as the troche form of clotrimazole was easier to administer and less costly than nystatin oral suspension. An open study designed to compare the effectiveness and safety of clotrimazole troches with nystatin oral suspension in the prevention of oropharyngeal candidiasis was conducted. ![]()
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